Adipolean (Variant) anticorps

N° du produit ABIN636638

L’anticorps Lapin Polyclonal anti- a été validé pour ELISA, WB et Inhibition. Il convient pour détecter dans des échantillons de Humain.

Aperçu rapide pour Adipolean (Variant) anticorps (ABIN636638)

Antigène: Adipolean

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)

Détail du produit

Épitope: Variant

Purification: Purified

Immunogène: Adipolean Variant antibody was raised in rabbit using highly pure recombinant human adipolean variant as the immunogen.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détail du antigène

Antigène: Adipolean

Sujet: The adipolean variant is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. It stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. The adipolean variant antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway.